Product Name :
Thy-1 (human):Fc (human), (recombinant)
Sequence:
Purity:
≥90% (SDS-PAGE)
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Use/Stability :
Stable for at least 6 months after receipt when stored at -20°C.
Description:
Human Thy-1 is a glycosyl phosphatidylinositol (GPI)- anchored glycoprotein of the immunoglobulin superfamily expressed in various cell types, particularly in cells of the neuronal system, activited microvascular endothelial cells, fibroblasts and blood stem cells.16561-29-8 Technical Information Thy-1 is involved in cell adhesion.1771691-34-9 In Vitro Human Thy-1 interacts with the integrin αvβ3 (CD51/CD61) and Mac-1 (CD11b/CD18).PMID:30969597 In astrocytes, binding of Thy-1 to beta3-integrin promotes focal adhesion formation. Historical results have shown that human Thy-1 binds to human αvβ3 integrin. SDS-PAGE analysis of Prod. No. ALX-522-091: Lane 1: MW marker, Lane 2: 0.1, Lane 3: 0.5, Labe 4: 1 µg Thy-1 (human):Fc (human), (recombinant). SDS-PAGE analysis of Prod. No. ALX-522-091: Lane 1: MW marker, Lane 2: 0.1, Lane 3: 0.5, Labe 4: 1 µg Thy-1 (human):Fc (human), (recombinant).
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Additional Information :
| Alternative Name CD90 | Concentration 1mg/ml after reconstitution. | Endotoxin Content | Formulation Lyophilized. Contains PBS. | Purity ≥90% (SDS-PAGE) | Reconstitution Reconstitute with 50µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein. | Source Produced in HEK 293 cells. The extracellular domain of human Thy-1 (aa 20-130) is fused to the Fc portion of human IgG1. | UniProt ID P04216