Eir fluid volume and electrolyte status. The decision to transfuse packed red blood cells (PRBC) was made according to the criteria of the ML 281 web attending physician or whenever a patient’s hemoglobin level dropped below 8 g/dL [23]. Patients with bacterial infections on admission and patients who developed bacterial infections during hospitalization were treated with appropriate empiric antibiotic therapy according to culture results and the results of appropriate diagnostic methods. When acute renal failure was severe or progressive and measures to improve renal function had been unsuccessful, renal replacement therapy was performed [4].DefinitionsCirrhosis was diagnosed on the basis of the results of liver histology or a combination of physical signs and symptoms and findings from biochemical analysis and ultrasonography. Acute kidney injury was defined as a 50 increase in serum creatinine (SCr) level or an immediate requirement for renal replacement therapy. The measurement of SCr levels was repeated following the withdrawal of diuretics in the patients. A study stated that aNew Score in Cirrhosis with AKITable 1. Patients’ demographic data and clinical characteristics.All patients (n = 190) Age (years) Gender (M/F) buy 3PO Length of ICU stay (days) Length of hospital stay (days) Serum Creatinine, ICU first day (mg/dL) MAP, ICU admission (mmHg) Glasgow coma scale, ICU admission Leukocytes, ICU first day (g/dL) Haemoglobin, ICU first day (g/dL) Albumin, ICU first day (g/dL) Sodium, ICU first day (mmol/L) Bilirubin, ICU first day (umol/L) [median] Prothrombin time INR, ICU first day [median] AST, ICU first day (units/L) [median] ALT, ICU first day (units/L) [median] Platelets, ICU first day (6109/L) [median] DM (Yes/No) Previous ascites (Yes/No) Previous SBP (Yes/No) Previous hepatic encephalopathy (Yes/No) Previous EV bleeding (Yes/No) Previous peptic ulcer bleeding (Yes/No) Previous hepatoma (Yes/No) Previous renal failure (Yes/No) Respiratory failure, ICU first day (Yes/No) Sepsis, ICU admission (\Yes/No) Child-Pugh points (mean6 SD) MELD score (mean 6 SD) APACHE II (mean 6 SD) APACHE III (mean 6 SD) SOFA (mean 6 SD) 5861 141/49 969 25625 3.262.4 73618 965 12.868.0 9.262.2 2.560.5 135617 11.2 [5.4] 2.8 [2.3] 530 [94] 182 [45] 95 [73] 52/138 94/96 39/150 116/74 86/104 59/131 59/131 57/133 37/153 71/119 11.862.1 33.261.1 25.560.77 106.063.19 11.660.Survivors (n = 51) 5862 41/10 664 32633 2.562.2 86616 1065 10.065.8 9.061.9 2.660.6 13869 4.6 [3.1] 1.9 [1.6] 133 [67] 56 [32] 91 [73] 14/37 20/31 8/43 29/22 23/28 17/34 10/41 17/34 4/47 11/40 11.062.4 24.768.8 20.966.9 77.9629.1 8.0662.Non-survivors (n = 139) 5961 100/39 10611 23621 3.662.4 69617 965 13.968.5 9.262.4 2.460.5 134619 13.6 [8.7] 3.1 [2.3] 678 [100] 228 [53] 97 [69] 38/101 74/65 31/107 87/52 63/76 42/97 49/90 40/99 33/106 60/79 12.062.0 35.8611.3 26.968.5 114.7632.6 12.963.p-valueNS (0.738) NS (0.238) ,0.001 0.067 0.005 ,0.001 NS (0.104) 0.001 NS (0.480) NS (0.130) NS (0.151) ,0.001 0.002 0.008 0.002 NS (0.645) NS (0.988) NS (0.087) NS (0.307) NS (0.473) NS (0.978) NS (0.681) 0.039 NS (0.544) 0.014 0.006 0.036 ,0.001 0.001 ,0.001 ,0.Abbreviation: M, male; F, female; ICU, intensive care unit; MAP, mean arterial pressure; INR, international normalized ratio; AST, aspartate aminotransferase; ALT, alanine aminotransferase; DM, diabetes mellitus; SBP, spontaneous bacterial peritonitis; EV, esophageal varices; SD, standard derivation; NS, not significant; MELD, model for end-stage liver disease;.Eir fluid volume and electrolyte status. The decision to transfuse packed red blood cells (PRBC) was made according to the criteria of the attending physician or whenever a patient’s hemoglobin level dropped below 8 g/dL [23]. Patients with bacterial infections on admission and patients who developed bacterial infections during hospitalization were treated with appropriate empiric antibiotic therapy according to culture results and the results of appropriate diagnostic methods. When acute renal failure was severe or progressive and measures to improve renal function had been unsuccessful, renal replacement therapy was performed [4].DefinitionsCirrhosis was diagnosed on the basis of the results of liver histology or a combination of physical signs and symptoms and findings from biochemical analysis and ultrasonography. Acute kidney injury was defined as a 50 increase in serum creatinine (SCr) level or an immediate requirement for renal replacement therapy. The measurement of SCr levels was repeated following the withdrawal of diuretics in the patients. A study stated that aNew Score in Cirrhosis with AKITable 1. Patients’ demographic data and clinical characteristics.All patients (n = 190) Age (years) Gender (M/F) Length of ICU stay (days) Length of hospital stay (days) Serum Creatinine, ICU first day (mg/dL) MAP, ICU admission (mmHg) Glasgow coma scale, ICU admission Leukocytes, ICU first day (g/dL) Haemoglobin, ICU first day (g/dL) Albumin, ICU first day (g/dL) Sodium, ICU first day (mmol/L) Bilirubin, ICU first day (umol/L) [median] Prothrombin time INR, ICU first day [median] AST, ICU first day (units/L) [median] ALT, ICU first day (units/L) [median] Platelets, ICU first day (6109/L) [median] DM (Yes/No) Previous ascites (Yes/No) Previous SBP (Yes/No) Previous hepatic encephalopathy (Yes/No) Previous EV bleeding (Yes/No) Previous peptic ulcer bleeding (Yes/No) Previous hepatoma (Yes/No) Previous renal failure (Yes/No) Respiratory failure, ICU first day (Yes/No) Sepsis, ICU admission (\Yes/No) Child-Pugh points (mean6 SD) MELD score (mean 6 SD) APACHE II (mean 6 SD) APACHE III (mean 6 SD) SOFA (mean 6 SD) 5861 141/49 969 25625 3.262.4 73618 965 12.868.0 9.262.2 2.560.5 135617 11.2 [5.4] 2.8 [2.3] 530 [94] 182 [45] 95 [73] 52/138 94/96 39/150 116/74 86/104 59/131 59/131 57/133 37/153 71/119 11.862.1 33.261.1 25.560.77 106.063.19 11.660.Survivors (n = 51) 5862 41/10 664 32633 2.562.2 86616 1065 10.065.8 9.061.9 2.660.6 13869 4.6 [3.1] 1.9 [1.6] 133 [67] 56 [32] 91 [73] 14/37 20/31 8/43 29/22 23/28 17/34 10/41 17/34 4/47 11/40 11.062.4 24.768.8 20.966.9 77.9629.1 8.0662.Non-survivors (n = 139) 5961 100/39 10611 23621 3.662.4 69617 965 13.968.5 9.262.4 2.460.5 134619 13.6 [8.7] 3.1 [2.3] 678 [100] 228 [53] 97 [69] 38/101 74/65 31/107 87/52 63/76 42/97 49/90 40/99 33/106 60/79 12.062.0 35.8611.3 26.968.5 114.7632.6 12.963.p-valueNS (0.738) NS (0.238) ,0.001 0.067 0.005 ,0.001 NS (0.104) 0.001 NS (0.480) NS (0.130) NS (0.151) ,0.001 0.002 0.008 0.002 NS (0.645) NS (0.988) NS (0.087) NS (0.307) NS (0.473) NS (0.978) NS (0.681) 0.039 NS (0.544) 0.014 0.006 0.036 ,0.001 0.001 ,0.001 ,0.Abbreviation: M, male; F, female; ICU, intensive care unit; MAP, mean arterial pressure; INR, international normalized ratio; AST, aspartate aminotransferase; ALT, alanine aminotransferase; DM, diabetes mellitus; SBP, spontaneous bacterial peritonitis; EV, esophageal varices; SD, standard derivation; NS, not significant; MELD, model for end-stage liver disease;.