Escherichia coli Porcine reproductive and respiratory syndrome virus (PRRSV) Porcine circovirus type 2 (PCV2) Swine influenza virus (SIV) Classical swine fever virus (CSFV) SNDX-275 chemical information Actinobacillus pleuropneumoniae Streptococcus suis Salmonella Typhimurium Group BACTERIA VIRUS Hindex 106 95 Total Citations 24023 16398 Mean Citations ?SD 153.0 ?89.4 172.6 ?114.6 Mean Quartile ?SD 1.4 ?0.9 1.6 ?0.8 COUNTRIES 1st, 2nd and 3rd USA (42.4 ), GBR (18.9 ), CAN (6.6 ) USA (53.7 ), NLD (8.4 ), CAN (7.4 ) USA (31.8 ), ESP (17.6 ), GBR CAN (14.1 ) USA (60.7 ), GBR (11.4 ), CHN (8.9 ) NLD (34.7 ), DEU (26.4 ), USA (8.3 ) CAN (32.8 ), USA (23.4 ), CHE (15.6 ) CAN (32.5 ), NLD (24.2 ), CHN (9.7 ) USA (41.0 ), DNK (21.3 ), NLD GBR (8.2 ) NLD (25.9 ), USA (19.0 ), DEU (17.2 ) GBR (41.0 ), USA (25 ), DNK ESP (7.1 ) ESP (46.4 ), USA (25 ), GBR (21.4 ) USA (41.8 ), DNK (29.1 ), GBR (20 ) USA (41.1 ), GBR (17.6 ), BEL (7.8 ) NLD (35.2 ), DEU (15.7 ), USA (11.8 ) USA (36 ), GBR (22 ), DNK (6 ) USA (51.0 ), GBR (16.3 ), JPN (8.1 ) USA (36.7 ), JPN NLD (8.2 ) DNK (31.2 ), USA DEU (12.5 ) USA (28.6 ), GBR (19.0 ), DNK (11.9 ) USA (58.5 ), ESP GBR CAN (7.3 ) USA (52.7 ), NLD (7.5 ) REST 32.1 30.5VIRUS163.6 ?84.1.8 ?0.22.44 5 6 7VIRUS VIRUS BACTERIA BACTERIA BACTERIA79 72 64 6216008 8689 7740 10739202.6 ?295.6 120.7 ?66.9 120.9 ?100.6 74.6 ?83.4 131.8 ?105.1.3 ?0.7 1.3 ?0.6 1.6 ?1.0 1.6 ?0.9 1.4 ?0.19.0 30.6 28.2 33.6 21.39Aujeszky’s disease virus (ADV) Foot-and-mouth disease virus (FMDV) African swine fever virus (ASFV) Pig endogenous retrovirus (PERV) Mycoplasma hyopneumoniae Staphylococcus aureus Campylobacter jejuni Porcine rotavirus (PoRV) Hepatitis E virus (HEV) Enterococcus faecium and E. spp Pasteurella multocida Porcine parvovirus Infection (PPV) Toxoplasma gondiiVIRUS VIRUS58449886.2 ?29.5 119.7 ?61.1.6 ?0.9 1.6 ?0.37.9 19.811 12 13 14 15 16 17 18 19 20VIRUS VIRUS BACTERIA BACTERIA BACTERIA VIRUS VIRUS BACTERIA BACTERIA VIRUS OTHER56 55 51 51 50 49 49 47 42 414802 7578 7392 6742 7423 5049 6392 6052 4251 321885.7 ?47.8 137.8 ?128.8 62.6 ?76.5 78.4 ?58.5 65.7 ?57.4 103.0 ?67.7 130.4 ?105.5 67.2 ?59.2 48.9 ?19.9 78.5 ?62.5 93.0 ?164.1.7 ?0.9 1.4 ?0.7 1.5 ?0.8 1.2 ?0.7 1.5 ?0.7 1.4 ?0.6 1.7 ?0.9 1.2 ?0.4 2.0 ?1.2 1.5 ?0.6 1.7 ?0.7.2 9.1 33.5 37.3 36.0 24.6 46.9 43.8 40.5 19.6 39.8From those included in group Other, pathogen with the AZD1722 chemical information highest H-indexdoi:10.1371/journal.pone.0149690.tPLOS ONE | DOI:10.1371/journal.pone.0149690 March 1,7 /H-Index in Swine DiseasesFig 2. Box plot showing H-index score quartiles by taxonomic division. + Mean. a>b (P<0.001). doi:10.1371/journal.pone.0149690.gwas Toxoplasma gondii found in rank 22 (H-index = 40), followed closely by Taenia solium (Cysticercus cellulosae) (rank 23; H-index = 38). Considering all the infectious agents included in the study, 9 out of 86 (10.5 ) classified as zoonotic, 2 out of 19 (10.5 ) considered emerging, and 5 out of 24 OIE-listed (20.8 ) were in the top 20. The remaining 4 agents in the top 20 were non-zoonotic, non-emerging and nonOIE-listed. About 40 of the 52 diseases contained in the DISCONTOOLS database affect pigs and, therefore, they were included in the present study. Of these, 13 diseases were identified in the list of pathogens with the highest 20 H-indices. Within the ten pathogens with SART.S23503 the highest Hindex, eight were included in DISCONTOOLS. The higher the H-index, the more papers sum for the total number of citations. Nevertheless, some pathogens with a low H-ind.Escherichia coli Porcine reproductive and respiratory syndrome virus (PRRSV) Porcine circovirus type 2 (PCV2) Swine influenza virus (SIV) Classical swine fever virus (CSFV) Actinobacillus pleuropneumoniae Streptococcus suis Salmonella Typhimurium Group BACTERIA VIRUS Hindex 106 95 Total Citations 24023 16398 Mean Citations ?SD 153.0 ?89.4 172.6 ?114.6 Mean Quartile ?SD 1.4 ?0.9 1.6 ?0.8 COUNTRIES 1st, 2nd and 3rd USA (42.4 ), GBR (18.9 ), CAN (6.6 ) USA (53.7 ), NLD (8.4 ), CAN (7.4 ) USA (31.8 ), ESP (17.6 ), GBR CAN (14.1 ) USA (60.7 ), GBR (11.4 ), CHN (8.9 ) NLD (34.7 ), DEU (26.4 ), USA (8.3 ) CAN (32.8 ), USA (23.4 ), CHE (15.6 ) CAN (32.5 ), NLD (24.2 ), CHN (9.7 ) USA (41.0 ), DNK (21.3 ), NLD GBR (8.2 ) NLD (25.9 ), USA (19.0 ), DEU (17.2 ) GBR (41.0 ), USA (25 ), DNK ESP (7.1 ) ESP (46.4 ), USA (25 ), GBR (21.4 ) USA (41.8 ), DNK (29.1 ), GBR (20 ) USA (41.1 ), GBR (17.6 ), BEL (7.8 ) NLD (35.2 ), DEU (15.7 ), USA (11.8 ) USA (36 ), GBR (22 ), DNK (6 ) USA (51.0 ), GBR (16.3 ), JPN (8.1 ) USA (36.7 ), JPN NLD (8.2 ) DNK (31.2 ), USA DEU (12.5 ) USA (28.6 ), GBR (19.0 ), DNK (11.9 ) USA (58.5 ), ESP GBR CAN (7.3 ) USA (52.7 ), NLD (7.5 ) REST 32.1 30.5VIRUS163.6 ?84.1.8 ?0.22.44 5 6 7VIRUS VIRUS BACTERIA BACTERIA BACTERIA79 72 64 6216008 8689 7740 10739202.6 ?295.6 120.7 ?66.9 120.9 ?100.6 74.6 ?83.4 131.8 ?105.1.3 ?0.7 1.3 ?0.6 1.6 ?1.0 1.6 ?0.9 1.4 ?0.19.0 30.6 28.2 33.6 21.39Aujeszky’s disease virus (ADV) Foot-and-mouth disease virus (FMDV) African swine fever virus (ASFV) Pig endogenous retrovirus (PERV) Mycoplasma hyopneumoniae Staphylococcus aureus Campylobacter jejuni Porcine rotavirus (PoRV) Hepatitis E virus (HEV) Enterococcus faecium and E. spp Pasteurella multocida Porcine parvovirus Infection (PPV) Toxoplasma gondiiVIRUS VIRUS58449886.2 ?29.5 119.7 ?61.1.6 ?0.9 1.6 ?0.37.9 19.811 12 13 14 15 16 17 18 19 20VIRUS VIRUS BACTERIA BACTERIA BACTERIA VIRUS VIRUS BACTERIA BACTERIA VIRUS OTHER56 55 51 51 50 49 49 47 42 414802 7578 7392 6742 7423 5049 6392 6052 4251 321885.7 ?47.8 137.8 ?128.8 62.6 ?76.5 78.4 ?58.5 65.7 ?57.4 103.0 ?67.7 130.4 ?105.5 67.2 ?59.2 48.9 ?19.9 78.5 ?62.5 93.0 ?164.1.7 ?0.9 1.4 ?0.7 1.5 ?0.8 1.2 ?0.7 1.5 ?0.7 1.4 ?0.6 1.7 ?0.9 1.2 ?0.4 2.0 ?1.2 1.5 ?0.6 1.7 ?0.7.2 9.1 33.5 37.3 36.0 24.6 46.9 43.8 40.5 19.6 39.8From those included in group Other, pathogen with the highest H-indexdoi:10.1371/journal.pone.0149690.tPLOS ONE | DOI:10.1371/journal.pone.0149690 March 1,7 /H-Index in Swine DiseasesFig 2. Box plot showing H-index score quartiles by taxonomic division. + Mean. a>b (P<0.001). doi:10.1371/journal.pone.0149690.gwas Toxoplasma gondii found in rank 22 (H-index = 40), followed closely by Taenia solium (Cysticercus cellulosae) (rank 23; H-index = 38). Considering all the infectious agents included in the study, 9 out of 86 (10.5 ) classified as zoonotic, 2 out of 19 (10.5 ) considered emerging, and 5 out of 24 OIE-listed (20.8 ) were in the top 20. The remaining 4 agents in the top 20 were non-zoonotic, non-emerging and nonOIE-listed. About 40 of the 52 diseases contained in the DISCONTOOLS database affect pigs and, therefore, they were included in the present study. Of these, 13 diseases were identified in the list of pathogens with the highest 20 H-indices. Within the ten pathogens with SART.S23503 the highest Hindex, eight were included in DISCONTOOLS. The higher the H-index, the more papers sum for the total number of citations. Nevertheless, some pathogens with a low H-ind.

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