Product Name :
p-MPPI hydrochloride
Description:
p-MPPI hydrochloride is a selective 5-HT1A receptor antagonist with high affinity for 5-HT1A receptors. p-MPPI hydrochloride can crosses the blood-brain barrier, and has clear antidepressant and anxiolytic-like effects.
CAS:
220643-77-6
Molecular Weight:
578.87
Formula:
C25H28ClIN4O2
Chemical Name:
4-iodo-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)benzamide hydrochloride
Smiles :
Cl.COC1=CC=CC=C1N1CCN(CCN(C(=O)C2C=CC(I)=CC=2)C2=CC=CC=N2)CC1
InChiKey:
PBPBIDMIRMWUCI-UHFFFAOYSA-N
InChi :
InChI=1S/C25H27IN4O2.ClH/c1-32-23-7-3-2-6-22(23)29-17-14-28(15-18-29)16-19-30(24-8-4-5-13-27-24)25(31)20-9-11-21(26)12-10-20;/h2-13H,14-19H2,1H3;1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
p-MPPI hydrochloride is a selective 5-HT1A receptor antagonist with high affinity for 5-HT1A receptors. p-MPPI hydrochloride can crosses the blood-brain barrier, and has clear antidepressant and anxiolytic-like effects.|Product information|CAS Number: 220643-77-6|Molecular Weight: 578.87|Formula: C25H28ClIN4O2|Chemical Name: 4-iodo-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)benzamide hydrochloride|Smiles: Cl.COC1=CC=CC=C1N1CCN(CCN(C(=O)C2C=CC(I)=CC=2)C2=CC=CC=N2)CC1|InChiKey: PBPBIDMIRMWUCI-UHFFFAOYSA-N|InChi: InChI=1S/C25H27IN4O2.{{Histamine} site|{Histamine} Neuronal Signaling|{Histamine} Protocol|{Histamine} In stock|{Histamine} manufacturer|{Histamine} Autophagy} ClH/c1-32-23-7-3-2-6-22(23)29-17-14-28(15-18-29)16-19-30(24-8-4-5-13-27-24)25(31)20-9-11-21(26)12-10-20;/h2-13H,14-19H2,1H3;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 17.{{Phenacetin} medchemexpress|{Phenacetin} COX|{Phenacetin} Protocol|{Phenacetin} Data Sheet|{Phenacetin} custom synthesis|{Phenacetin} Autophagy} 86 mg/mL (30.PMID:24367939 85 mM; Need ultrasonic). H2O : 3.33 mg/mL (5.75 mM; ultrasonic and warming and heat to 60°C).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|p-MPPI hydrochloride has no agonist activity in both in vitro and in vivo tests of pre- and post-synaptic 5-HT1A receptor activity.|In Vivo:|p-MPPI hydrochloride (0.5-4.5 mg/kg; i.p.) shows anxiolytic-like profile in the murine elevated plus-maze.|Products are for research use only. Not for human use.|