Product Name :
ZD 7155 HCl
Description:
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
CAS:
146709-78-6
Molecular Weight:
474.99
Formula:
C26H27ClN6O
Chemical Name:
5,7-diethyl-1-{[2′-(1H-1,2,3,4-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl]methyl}-1,2,3,4-tetrahydro-1,6-naphthyridin-2-one hydrochloride
Smiles :
Cl.CCC1=CC2=C(CCC(=O)N2CC2C=CC(=CC=2)C2=CC=CC=C2C2NN=NN=2)C(CC)=N1
InChiKey:
NAGGAAHTUXEGFG-UHFFFAOYSA-N
InChi :
InChI=1S/C26H26N6O.{{Esomeprazole} web|{Esomeprazole} Proton Pump|{Esomeprazole} Technical Information|{Esomeprazole} Description|{Esomeprazole} custom synthesis|{Esomeprazole} Epigenetics} ClH/c1-3-19-15-24-22(23(4-2)27-19)13-14-25(33)32(24)16-17-9-11-18(12-10-17)20-7-5-6-8-21(20)26-28-30-31-29-26;/h5-12,15H,3-4,13-14,16H2,1-2H3,(H,28,29,30,31);1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.|Product information|CAS Number: 146709-78-6|Molecular Weight: 474.99|Formula: C26H27ClN6O|Chemical Name: 5,7-diethyl-1-{[2′-(1H-1,2,3,4-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl]methyl}-1,2,3,4-tetrahydro-1,6-naphthyridin-2-one hydrochloride|Smiles: Cl.CCC1=CC2=C(CCC(=O)N2CC2C=CC(=CC=2)C2=CC=CC=C2C2NN=NN=2)C(CC)=N1|InChiKey: NAGGAAHTUXEGFG-UHFFFAOYSA-N|InChi: InChI=1S/C26H26N6O.ClH/c1-3-19-15-24-22(23(4-2)27-19)13-14-25(33)32(24)16-17-9-11-18(12-10-17)20-7-5-6-8-21(20)26-28-30-31-29-26;/h5-12,15H,3-4,13-14,16H2,1-2H3,(H,28,29,30,31);1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (526.33 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Trastuzumab emtansine (solution)} MedChemExpress|{Trastuzumab emtansine (solution)} Antibody-drug Conjugate/ADC Related|{Trastuzumab emtansine (solution)} Purity & Documentation|{Trastuzumab emtansine (solution)} Description|{Trastuzumab emtansine (solution)} manufacturer|{Trastuzumab emtansine (solution)} Cancer} |Shelf Life: ≥12 months if stored properly.PMID:24818938 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|ZD 7155 and losartan behave as competitive antagonists and the pressor response curve to angiotensin II is shifted to the right in conscious SD rats. Experiments in conscious SD rats also show that ZD 7155 is approximately ten times as potent as losartan in suppressing the angiotensin II-induced pressor response (240 ng/kg; 10 min infusion).|References:|Junggren IL, et al. Comparative cardiovascular effects of the angiotensin II type 1 receptor antagonists ZD 7155 and losartan in the rat. J Pharm Pharmacol. 1996 Aug;48(8):829-33.Products are for research use only. Not for human use.|