Product Name :
[Met5]-Enkephalin, amide
Description:
[Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors.
CAS:
60117-17-1
Molecular Weight:
572.68
Formula:
C27H36N6O6S
Chemical Name:
(2S)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]acetamido}acetamido)-3-phenylpropanamido]-4-(methylsulfanyl)butanamide
Smiles :
CSCC[C@H](NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC1C=CC(O)=CC=1)C(N)=O
InChiKey:
HBDDEVHKKBWEQT-FKBYEOEOSA-N
InChi :
InChI=1S/C27H36N6O6S/c1-40-12-11-21(25(29)37)33-27(39)22(14-17-5-3-2-4-6-17)32-24(36)16-30-23(35)15-31-26(38)20(28)13-18-7-9-19(34)10-8-18/h2-10,20-22,34H,11-16,28H2,1H3,(H2,29,37)(H,30,35)(H,31,38)(H,32,36)(H,33,39)/t20-,21-,22-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine} site|{1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine} Liposome|{1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine} Biological Activity|{1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine} Formula|{1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine} custom synthesis|{1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
[Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors.|Product information|CAS Number: 60117-17-1|Molecular Weight: 572.{{Pritelivir} MedChemExpress|{Pritelivir} Anti-infection|{Pritelivir} Protocol|{Pritelivir} References|{Pritelivir} supplier|{Pritelivir} Epigenetics} 68|Formula: C27H36N6O6S|Chemical Name: (2S)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]acetamido}acetamido)-3-phenylpropanamido]-4-(methylsulfanyl)butanamide|Smiles: CSCC[C@H](NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC1C=CC(O)=CC=1)C(N)=O|InChiKey: HBDDEVHKKBWEQT-FKBYEOEOSA-N|InChi: InChI=1S/C27H36N6O6S/c1-40-12-11-21(25(29)37)33-27(39)22(14-17-5-3-2-4-6-17)32-24(36)16-30-23(35)15-31-26(38)20(28)13-18-7-9-19(34)10-8-18/h2-10,20-22,34H,11-16,28H2,1H3,(H2,29,37)(H,30,35)(H,31,38)(H,32,36)(H,33,39)/t20-,21-,22-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23626759 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|[Met5]-Enkephalin at 0.1 nM, 10 nM, and 1 μM significantly reduces the total number of glial cells in culture. [Met5]-Enkephalin, amide acts via δ-opioid receptor to inhibit pelvic nerve-evoked contractions of cat distal colon. [Met5]-enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC50 value of 2.2 nM. [Met5]enkephalin at a concentration (3 nM) which produces a large inhibition of neurogenic contractions, has no effect on contractions to exogenous acetylcholine.|Products are for research use only. Not for human use.|