Product Name :
CT-721
Description:
CT-721 is a potent and time-dependent Bcr-Abl kinase inhibitor with an IC50 of 21.3 nM for wild-type Bcr-Abl kinase, and possesses anti-chronic myeloid leukemia (CML) activities.
CAS:
1388710-60-8
Molecular Weight:
525.04
Formula:
C30H29ClN6O
Chemical Name:
N-[3-(2-{6-chloroimidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methylphenyl]-1-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-indene-5-carboxamide
Smiles :
CN1CCN(CC1)C1CCC2=CC(=CC=C21)C(=O)NC1=CC(C#CC2=CN=C3C=CC(Cl)=NN32)=C(C)C=C1
InChiKey:
UKRXMBYVZRAMAF-UHFFFAOYSA-N
InChi :
InChI=1S/C30H29ClN6O/c1-20-3-7-24(18-21(20)4-8-25-19-32-29-12-11-28(31)34-37(25)29)33-30(38)23-5-9-26-22(17-23)6-10-27(26)36-15-13-35(2)14-16-36/h3,5,7,9,11-12,17-19,27H,6,10,13-16H2,1-2H3,(H,33,38)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Racotumomab} site|{Racotumomab} Technical Information|{Racotumomab} Data Sheet|{Racotumomab} custom synthesis|{Racotumomab} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Dostarlimab} site|{Dostarlimab} Immunology/Inflammation|{Dostarlimab} Biological Activity|{Dostarlimab} Data Sheet|{Dostarlimab} custom synthesis|{Dostarlimab} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:31536241
Additional information:
CT-721 is a potent and time-dependent Bcr-Abl kinase inhibitor with an IC50 of 21.3 nM for wild-type Bcr-Abl kinase, and possesses anti-chronic myeloid leukemia (CML) activities.|Product information|CAS Number: 1388710-60-8|Molecular Weight: 525.04|Formula: C30H29ClN6O|Chemical Name: N-[3-(2-{6-chloroimidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methylphenyl]-1-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-indene-5-carboxamide|Smiles: CN1CCN(CC1)C1CCC2=CC(=CC=C21)C(=O)NC1=CC(C#CC2=CN=C3C=CC(Cl)=NN32)=C(C)C=C1|InChiKey: UKRXMBYVZRAMAF-UHFFFAOYSA-N|InChi: InChI=1S/C30H29ClN6O/c1-20-3-7-24(18-21(20)4-8-25-19-32-29-12-11-28(31)34-37(25)29)33-30(38)23-5-9-26-22(17-23)6-10-27(26)36-15-13-35(2)14-16-36/h3,5,7,9,11-12,17-19,27H,6,10,13-16H2,1-2H3,(H,33,38)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|