Product Name :
Rocaglamide
Sequence:
Purity:
≥98% (HPLC)
Molecular Weight:
505.6
Solubility :
Soluble in DMSO, 100% ethanol or methanol.
Appearance:
White to off-white sticky solid.68047-06-3 medchemexpress
Use/Stability :
As indicated on product label or CoA when stored as recommended.1855925-27-7 Formula
Description:
NF-κB inhibitor Immunosuppressant. Potent inhibitor of NF-κB activation in T cells, with an almost complete inhibition at 200nM. Suppresses cytokine production (IFN-γ, TNF-α, IL-2 and IL-4) and inhibits NF-AT in peripheral blood T cells at concentrations that do not impair NF-κB and AP-1 activities. In contrast to the immunosuppressant cyclosporin A , rocaglamide does not inhibit calcineurin phosphatase activity. Induces apoptosis.
CAS :
84573-16-0
Solubility:
Soluble in DMSO, 100% ethanol or methanol.PMID:30137808
Formula:
C29H31NO7
Additional Information :
| Alternative Name Rocaglamide A | Appearance White to off-white sticky solid. | CAS 84573-16-0 | Couple Target NF-kappaB | Couple Type Inhibitor | Formula C29H31NO7 | MW 505.6 | Purity ≥98% (HPLC) | Solubility Soluble in DMSO, 100% ethanol or methanol. | Source Synthetic | Unit of Measure (UM) µg