Product Name :
Lusianthridin
Description:
Lusianthridin, a pure compound from Dendrobium venustum, have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling.
CAS:
87530-30-1
Molecular Weight:
242.27
Formula:
C15H14O3
Chemical Name:
7-methoxy-9, 10-dihydrophenanthrene-2, 5-diol
Smiles :
COC1=CC2CCC3=CC(O)=CC=C3C=2C(O)=C1
InChiKey:
RDKDIPDDUFMMMT-UHFFFAOYSA-N
InChi :
InChI=1S/C15H14O3/c1-18-12-7-10-3-2-9-6-11(16)4-5-13(9)15(10)14(17)8-12/h4-8,16-17H,2-3H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Ingenol Mebutate web
Shelf Life:
≥360 days if stored properly.Faricimab VEGFR
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33269617
Additional information:
Lusianthridin, a pure compound from Dendrobium venustum, have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling.|Product information|CAS Number: 87530-30-1|Molecular Weight: 242.27|Formula: C15H14O3|Chemical Name: 7-methoxy-9, 10-dihydrophenanthrene-2, 5-diol|Smiles: COC1=CC2CCC3=CC(O)=CC=C3C=2C(O)=C1|InChiKey: RDKDIPDDUFMMMT-UHFFFAOYSA-N|InChi: InChI=1S/C15H14O3/c1-18-12-7-10-3-2-9-6-11(16)4-5-13(9)15(10)14(17)8-12/h4-8,16-17H,2-3H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells. Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively.|References:|Narumol Bhummaphan, et al. Targeting of Lung Cancer Stem Cells via Src-STAT3 Suppression. Phytomedicine. 2019 Sep;62:152932.Products are for research use only. Not for human use.|