Product Name :
Br-PEG3-MS
Description:
Br-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
Molecular Weight:
291.16
Formula:
C7H15BrO5S
Chemical Name:
2-[2-(2-bromoethoxy)ethoxy]ethyl methanesulfonate
Smiles :
CS(=O)(=O)OCCOCCOCCBr
InChiKey:
NKBMJZIHSUUABO-UHFFFAOYSA-N
InChi :
InChI=1S/C7H15BrO5S/c1-14(9,10)13-7-6-12-5-4-11-3-2-8/h2-7H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.SQ109 supplier
Shelf Life:
≥12 months if stored properly.TLQP-21 TGF-beta/Smad
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Br-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.PMID:31747199 |Product information|Molecular Weight: 291.16|Formula: C7H15BrO5S|Chemical Name: 2-[2-(2-bromoethoxy)ethoxy]ethyl methanesulfonate|Smiles: CS(=O)(=O)OCCOCCOCCBr|InChiKey: NKBMJZIHSUUABO-UHFFFAOYSA-N|InChi: InChI=1S/C7H15BrO5S/c1-14(9,10)13-7-6-12-5-4-11-3-2-8/h2-7H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|References:|An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562Products are for research use only. Not for human use.|