In Drosophila melanogaster genetic manipulation of neurons expressing AST-A repress foodstuff ingestion and responsiveness to sugar [23] and ablation of AST-A and its receptor (DAR-1) appreciably reduce larval foraging behaviour in the existence of food items [27]
Form A allatostatins (AST-As) are a family of insect peptides with a conserved C-terminal FGL-amide motif. They have been originally isolated from the cockroach Diploptera punctata but are common in…